PEYRONIE’S DISEASE

WHAT IS PEYRONIE’S DISEASE?

Named after French surgeon François Gigot de la Peyronie, Peyronie’s disease is a penile condition characterised by a significant bend in the penis shaft, caused by a connective tissue disorder where scar tissue (fibrous plaque) grows on the penis. Peyronie’s disease can cause pain and in extreme cases prevent you from enjoying sex. 5% of men are affected by Peyronie’s disease, and the condition can become chronic over time if not treated. Other symptoms of the disease may include erectile dysfunction, pain during erection and loss of penis girth and length.

WHAT ARE THE SYMPTOMS OF PEYRONIE’S DISEASE?

These are the most common symptoms for Peyronie’s disease:
If you have any of these symptoms, it’s best to get them checked out by your GP.

WHAT CAN CAUSE PEYRONIE’S DISEASE?

There is no official conclusion about what causes Peyronie’s disease. However, there are two main explanations that are backed in the field:

  1. The scar tissue, fibrous plaque, starts forming after hitting or bending the penis during an accident, which causes internal bleeding in the penis. For example, this could happen during sex when the erect penis bends sharply. Blood can build up under the skin or in the penis and cause pain. Accidents during sport or even car accidents can cause scar tissue in the penis. These incidents are also called penile fractures.
  2. Another explanation is that the condition is due to a combination of injury and inherited genes. This means the person in question is more vulnerable for developing Peyronie’s after having an accident in the penile area. However, there’s not enough research to claim that this is the main cause of Peyronie’s disease.

HOW IS PEYRONIE’S DISEASE DIAGNOSED?

In most cases, there will be a particular technique to determine where the scar tissue that causes Peyronie’s is situated in the penis. There are three methods to diagnose Peyronie’s disease:

  1. Before rushing to a doctor try to diagnose Peyronie’s for yourself. Over ¼ of all men are born with a curved penis which is not dangerous at all. But if you experience an extreme bend in your penis or one of the above mentioned symptoms you might have Peyronie’s disease.
  2. If you’re experiencing some of the symptoms of Peyronie’s disease, we recommend to visit your GP for a physical examination. The doctor will determine the place of the scar tissue and the degree of the curvature.
  3. Other tests, such as an ultrasound echo, can be carried out to see where the scar tissue is situated in the penis. With an ultrasound, the echo of sound waves can create an image of the penis’ soft tissue, where it’s clear to see if there’s any scar tissue.

HOW IS PEYRONIE'S DISEASE TREATED?

There are multiple treatments for Peyronie’s disease, each one different depending on the scar tissue condition of the penis. In the table below you will find the most common treatment methods:

PENILE TRACTION

Penis traction is the safest and most effective method for a natural penis enlargement. Due to phalogenic traction, the penis stretches continuously and will eventually enlarge and straighten any bends associated with conditions such as Peyronie’s disease. Penis extenders use phalogenic traction in a safe and natural way to give you the best result. Learn more about penis traction.

MEDICATION

Some medications, such as Pentoxifylline, can reduce the scar tissue over a long period of time, but won’t treat the whole curvature of the penis. Other drugs can help reduce curvature and pain in the short term, but it’s not a long term solution.

PENILE SURGERY

Surgery is not the first recommended option because there’s always complication risks at hand. Most men who choose surgery have high expectations of a big increase in length and reduction of curvature, however they’re reportedly mostly disappointed afterwards about the results. There are also multiple risks depending on the kind of surgery. Shrinkage during recovery or even erectile dysfunction can arise after penile surgery. Read more about penis enlargement surgery here.

IONTOPHORESIS

A technique that uses an electric current to treat the scar tissue. However, the treatment doesn’t have enough conclusive results to really be sure it’s effective.

SHOCK WAVE THERAPY

Sound waves are used to break up the scar tissue cells. This treatment is still not completely researched and therefore its effectiveness is unknown.

Read the following text if you want to find out more about the study that was conducted that proves the Jes-Extender can help with the treatment of Peyronie’s disease.

TREATMENT OF PEYRONIE’S DISEASE VIA MECHANICAL TRACTION, MaleEdge™

A prospective study in 26 males

INTRODUCTION: The traction force applied upon the tissues results in an adaptation reaction at a structural level, due to the suppression of an inhibitor factor related with cellular division, which thereby results in cellular duplication and therefore, the expansion of the tissues. This principle has successfully been applied for quite some time for different medical purposes, among which the treatment of skin lesions, the loss of tissue and post-radiation scars are the most important. The origin of the fibrotic plaque in Peyronie’s disease still remains an unanswered question. The histological studies carried out so far confirm the presence of high concentrations of type-III collagen in the plaque, having been compared with hyperplastic scar tissue and keloids. The “maturation” of the fibrous tissue scars is produced via the translocation of collagen fibers, which takes place secondary to the traction forces that the fibroblasts oppose to the cellular contraction forces. The higher the concentration of type-III collagen in the fibrotic tissue, the stronger the contraction force is. The continuous mechanical traction on the penis in Peyronie’s disease stimulates cellular division and, therefore, the expansion of the healthy tissues and finally exerts an opposing force to the contraction force of the collagen.

POPULATION AND METHODS: A prospective study has been performed in 26 males who had been diagnosed as having Peyronie’s disease and were treated during a 6 month-period with the mechanical traction device, Jes Extender®, exerting a pressure in the range of 1,200 and 1,500 g. The mean age was 50.8 (30 – 68) years old and the mean evolution time of the disease was 25.6 (2 – 72) months. Multiple fibrotic plaques were identified in 6 cases and just one in 19 patients. The long axis of the plaque was equal to or less than 3 cm in 20 cases; 11 patients referred sensorial disturbances of the penis and 21 presented with erectile dysfunction.

OUTCOMES: Mean values of the assessed parameters before the enrollment, and at 3 and 6 months after treatment was performed are expressed in Table I.

CONCLUSIONS: After a 6-month treatment, the plaque disappeared in 7 cases (26.9%) and a marked decrease in the number, size and consistency of the plaque was observed in 18 (69.2%). Likewise, 13 (61.9%) patients recovered their erectile function and 10 (38.5%)recovered their sensitivity in the penis.

Pre-treatment 3 months 6 months
Curvature angle (º)
49.8 (27-63)
37.4 (18-54)
28.7 (5-48)
Size of plaque (cm)
2.35
1.77
1.15
Length in flaccidity (cm)
9.78
12.1
13.1
Length in erection (cm)
14.4 (10-19)
15.3
16.5
The mechanical traction on the penis has a beneficial effect on the fibrotic plaque that is usually clinically evident via the reduction of the size and consistency of the plaque, the correction of the curvature angle, the recovery of the length of the penis, and the improvement in the quality of the erection.
MaleEdge cannot be held responsible for any failure to treat Peyronie’s Disease.

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